Searchable abstracts of presentations at key conferences in endocrinology

ea0077p192 | Metabolism, Obesity and Diabetes | SFEBES2021

N-acetylmuramoyl-L-alanine amidase is a biomarker for remission of type 2 diabetes after bariatric surgery

Iqbal Zohaib , Fachim Helene , Gibson John , Baricevic-Jones Ivona , Campbell Amy , Geary Bethany , Donn Rachelle , Syed Akheel , Wetton Anthony , Soran Handrean , Heald Adrian

Aims: We used sequential window acquisition of all theoretical fragment ion spectra Mass Spectrometry (SWATH-MS) to identify proteins acting as markers of remission of type 2 diabetes (T2DM) in patients who lost weight after bariatric surgery.Background: Bariatric surgery results in remission of T2DM in up to 80% of patients. The mechanisms underpinning are largely unknown. N-acetylmuramoyl-L-alanine amidase (PGLRYP2) is an immune response enzyme that br...